Dynamic phosphorylation of CENP-N by CDK1 guides accurate chromosome segregation in mitosis

Ran Liu^1,2,† , Zhen Dou^1,2,† , Tian Tian^1,† , Xinjiao Gao^1,2 , Lili Chen¹ , Xiao Yuan^1,2 , Chunyue Wang¹ , Jiahe Hao¹ , Ping Gui^1,2,3 , McKay Mullen^1,3 , Felix Aikhionbare³ , Liwen Niu^1,2 , Guoqiang Bi^1,2 , Peng Zou⁴ , Xuan Zhang¹ , Chuanhai Fu^1,2 , Xuebiao Yao^1,2 , Jianye Zang^1,* , Xing Liu^1,2,*

¹MOE Key Laboratory for Cellular Dynamics & Hefei National Research Center for Interdisciplinary Sciences at the Microscale, University of Science and Technology of China School of Life Sciences, Hefei 230026, China
²CAS Center for Excellence in Molecular and Cell Sciences, Anhui Key Laboratory for Cellular Dynamics and Chemical Biology, Hefei 230027, China
³Keck Center for Cellular Dynamics, Morehouse School of Medicine, Atlanta, GA 30310, USA
⁴College of Chemistry and Molecular Engineering, Peking University, Beijing 100871, China
^†These authors contributed equally to this work
^*Correspondence to:Jianye Zang , Email:zangjy@ustc.edu.cn Xing Liu , Email:xing1017@ustc.edu.cn

J Mol Cell Biol, Volume 15, Issue 6, June 2023, mjad041,  https://doi.org/10.1093/jmcb/mjad041

Keyword: mitosis, centromere, CENP-N, CDK1, phosphorylation

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